Armed with the Cintiq 12WX I did my first fully digital drawing sketching first just like on paper, then doing some quick colouring. I am not that happy with how it went, though it does have a certain style going. I think I might try some more MedusaVamps - see if things get better and better.
I am getting better at the tablet, using the hotkeys to run both screens at once with the pen and such. Everyone should have one of these - awesome.